renal pathology

 
WISCONSIN DIAGNOSTIC LABORATORIES + MEDICAL COLLEGE OF WISCONSIN

Academic Renal Pathology Expertise

SUBSPECIALTY RENAL PATHOLOGY SERVICES

Concierge Renal Pathology.
Direct Specialist Collaboration.

Wisconsin Diagnostic Laboratories (WDL), in partnership with the Medical College of Wisconsin (MCW) Department of Pathology, delivers comprehensive local expertise in native and transplant kidney biopsy interpretation—backed by fellowship-trained renal pathologists, direct physician communication, and rapid turnaround times.

Renal Microscopic Analysis

Fellowship-Trained

Renal Pathology Specialists

24-Hour

Preliminary Diagnostic Turnaround

Tri-Modality

Light, IF & Electron Microscopy

Academic

Clinical Partnership with MCW

CLINICOPATHOLOGIC COLLABORATION

Concierge Care for Patients with Kidney Disease

 

Our concierge-level renal pathology service centers on individualized consultation for every case. We provide accurate, actionable diagnoses within 24 hours of specimen receipt and immediately communicate preliminary results directly to the treating physician.

 

We emphasize continuous clinicopathologic correlation, keeping lines of communication open so nephrologists and clinical teams have fast, clear diagnostic clarity when managing complex patient care.

 

Treating physicians have direct access to our renal pathologists via phone, text, email, or video conference for follow-up discussions and preliminary case reviews.

 

We also support multidisciplinary care by scheduling in-person or virtual kidney biopsy conferences tailored to your clinical group's needs.

PROGRAM OVERVIEW

Renal Pathology at WDL

COMPLETE DIAGNOSTIC CAPABILITIES

Comprehensive Tri-Modality Evaluation

Light Microscopy

Light Microscopy

Comprehensive histological analysis on native and transplant kidney tissues using serial sectioning and specialized histochemical staining protocols.

Immunofluorescence

Immunofluorescence

Rapid panel processing for immunoglobulins (IgG, IgA, IgM), complement components (C3, C1q), and kappa/lambda light chains to evaluate immune-mediated disease.

Electron Microscopy

Electron Microscopy

High-resolution transmission electron microscopy (TEM) in-house for evaluating ultrastructural basement membrane changes, podocyte effacement, and immune deposit localization.

ADVANCED LABORATORY MENU

Specialized Diagnostic & Ancillary Testing

Glomerular Disease Panel

PLA2R tissue staining for membranous nephropathy, and IgG subclass analysis (IgG1, IgG2, IgG3, IgG4).

Specialized Histochemistry

Congo Red staining with polarized light examination for amyloidosis detection, along with Paraffin Immunofluorescence when frozen tissue is insufficient.

Transplant & Autoimmune Menu

C4d immunohistochemistry / immunofluorescence, viral IHC (SV40/BK virus, CMV), and comprehensive antibody panel evaluations.

SUBSPECIALTY CONSULTATION SERVICES

Renal Pathology Consultation Services

 

WDL and MCW Renal Pathology provide consultative review services for diagnostically challenging or complex kidney biopsy cases, including glomerular diseases, transplant rejection, tubulointerstitial disorders, and rare vascular lesions. Consultative cases may be submitted for subspecialty review and clinicopathologic correlation through our pathology consultation program.

LOGISTICS & SPECIMEN HANDLING

Renal Biopsy Submission Protocol

Renal Biopsy Kits

Complimentary kit includes 10% NBF, Michel's Transport Medium, and Glutaraldehyde solution.*

*Refrigerate glutaraldehyde upon receipt.

Specimen Shipping & Delivery

Local courier pickup across Greater Milwaukee, plus expedited overnight shipping options for regional facilities.

Forms & Requisitions

Access requisition forms, safety data sheets, and online reporting portals for streamlined order entry.

OUR DIAGNOSTIC TEAM

Renal Pathology Specialists

Alexander J. Gallan, MD

Alexander J. Gallan, MD

Associate Professor of Pathology
Medical College of Wisconsin

Carl S. Dernell, MD

Carl S. Dernell, MD

Assistant Professor of Pathology
Medical College of Wisconsin

Partner with WDL & MCW Renal Pathology

Subspecialty academic expertise, 24-hour preliminary turnaround, and direct physician collaboration for your practice.